Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL165370 | 0.81 | ALDH1A1 (0.59) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL15592326 | 0.78 | TP53 (0.50) | ALDH1A1TSHRSMN1; SMN2TDP1TP53 | |
| SCHEMBL28295333 | 0.77 | ALDH1A1 (0.54) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL28296973 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL28295482 | 0.76 | ALDH1A1 (0.53) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL28614232 | 0.72 | TSHR (0.71) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL29387332 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL42787 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL8144263 | 0.72 | ALDH1A1 (1.00) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A | |
| SCHEMBL827863 | 0.72 | TSHR (0.70) | ALDH1A1TSHRMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5583188-A | USING TITANIUM, ORGANOALUMINUM, NITROGEN OR OXYGEN HETEROCYCLE CONTAINING CATALYST | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-10 | — | — | US | disclosed |
| EP-0086644-B1 | CATALYST COMPOSITION AND PROCESS FOR POLYMERIZING OLEFINS | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |
| EP-0086644-A2 | Catalyst composition and process for polymerizing olefins | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1983-08-24 | — | — | EP | disclosed |