Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936417 | 0.99 | HTR2C (0.32) | HTR2CHTR2BESR2 | |
| SCHEMBL8937658 | 0.94 | HTR2C (0.33) | HTR2CHTR2B | |
| SCHEMBL8936073 | 0.94 | HTR2C (0.33) | HTR2CHTR2BESR2PDE5AHDAC1 | |
| SCHEMBL8937813 | 0.93 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL8939225 | 0.91 | HTR2C (0.33) | HTR2CHTR2BESR2 | |
| SCHEMBL8939306 | 0.91 | HTR2C (0.33) | HTR2CHTR2BESR2 | |
| SCHEMBL8939399 | 0.91 | HTR2C (0.33) | HTR2CHTR2BESR2 | |
| SCHEMBL8932625 | 0.91 | PDE5A (0.35) | ESR2PDE5AHDAC1HDAC6 | |
| SCHEMBL8964118 | 0.91 | — | — | |
| SCHEMBL8964281 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |
| EP-2206695-A1 | TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2010-07-14 | — | — | EP | disclosed |