Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.30 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.30 |
| ▸ | MERTK | Q12866 | 1/20 | 0.30 |
| ▸ | GAS6 | Q14393 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939225 | 1.00 | HTR2C (0.33) | HTR2CHTR2BHTR2AESR2FLT3 | |
| SCHEMBL8939306 | 1.00 | HTR2C (0.33) | HTR2CHTR2BHTR2AESR2FLT3 | |
| SCHEMBL8939169 | 0.96 | HTR2C (0.34) | HTR2CHTR2BHTR2AESR2 | |
| SCHEMBL8937813 | 0.93 | HTR2C (0.32) | HTR2CHTR2B | |
| SCHEMBL8937658 | 0.92 | HTR2C (0.33) | HTR2CHTR2BHTR2A | |
| SCHEMBL8936417 | 0.92 | HTR2C (0.32) | HTR2CHTR2BESR2 | |
| SCHEMBL8939475 | 0.92 | GABRA1 (0.32) | ESR2 | |
| SCHEMBL8936261 | 0.91 | HTR2C (0.32) | HTR2CHTR2BESR2 | |
| SCHEMBL8969050 | 0.90 | HTR2C (0.32) | HTR2CHTR2BHTR2A | |
| SCHEMBL8968294 | 0.90 | HTR2C (0.32) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |