Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1803386 | 0.87 | HTR2B (0.48) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL656135 | 0.84 | HTR2B (0.42) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL656134 | 0.84 | HTR2B (0.42) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL652162 | 0.82 | HTR2B (0.68) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL13051513 | 0.82 | HTR2B (0.68) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL652161 | 0.82 | HTR2B (0.68) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL1807215 | 0.78 | HRH1 (0.54) | HRH1LMNAADRA1DADRA1A | |
| SCHEMBL987683 | 0.77 | ALDH1A1 (0.49) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL29412616 | 0.77 | ALDH1A1 (0.49) | HTR2BALDH1A1HRH1KMT2AKCNH2 | |
| SCHEMBL15473770 | 0.76 | HRH1 (0.43) | HRH1LMNAADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996031469-A1 | N-SUBSTITUTED AZAHETEROCYCLIC CARBOXYLIC ACIDS AND ESTERS THEREOF | NOVO NORDISK A/S (DK) | 1996-10-10 | — | — | WO | disclosed |