SCHEMBL8936371

SCHEMBL8936371

CCNS(=O)(=O)c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)c(F)cc1Cl

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
GAA P10253 1/20 0.34
ALOX5AP P20292 2/20 0.31
FEN1 P39748 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31588296 0.89 CYP3A4 (0.35) KDM4EALDH1A1
SCHEMBL29709281 0.87
SCHEMBL6640645 0.87
Hydrochloric Acid SCHEMBL31588401 0.87 ATM (0.30)
Hydrochloric Acid SCHEMBL31588282 0.86 ATM (0.33)
SCHEMBL3554522 0.84 CA1 (0.34)
SCHEMBL8936449 0.83 SMN1; SMN2 (0.35) KDM4EALDH1A1
SCHEMBL10695876 0.81 BCAT1 (0.34) GAA
SCHEMBL10695874 0.81 BCAT1 (0.34) GAA
SCHEMBL7951096 0.81 BRD9 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486610-A HERBICIDE INTERMEDIATES UNIROYAL CHEMICAL COMPANY, INC. (US) 1996-01-23 US disclosed
US-5324854-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1994-06-28 US disclosed
EP-0598774-A1 BENZENESULFONAMIDE DERIVATIVES AS HERBICIDES UNIROYAL CHEMICAL COMPANY, Inc. (US) 1994-06-01 EP disclosed
WO-1993003019-A1 BENZENESULFONAMIDE DERIVATIVES AS HERBICIDES UNIROYAL CHEMICAL COMPANY, INC. (US) 1993-02-18 WO disclosed
US-5169430-A Herbicides UNIROYAL CHEMICAL COMPANY, INC. (US) 1992-12-08 US disclosed