Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.71 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936580 | 0.87 | TACR1 (0.80) | TACR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8936463 | 0.85 | TACR1 (0.76) | TACR1ALDH1A1 | |
| SCHEMBL8936460 | 0.85 | TACR1 (0.76) | TACR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8936599 | 0.85 | TACR1 (0.76) | TACR1NPC1RAB9AALDH1A1 | |
| SCHEMBL8936576 | 0.83 | TACR1 (1.00) | TACR1MEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8936535 | 0.83 | TACR1 (0.73) | TACR1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL8936481 | 0.81 | TACR1 (0.86) | TACR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8936527 | 0.81 | TACR1 (0.90) | TACR1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL8936410 | 0.80 | TACR1 (0.72) | TACR1NPC1RAB9AALDH1A1 | |
| SCHEMBL8936536 | 0.80 | TACR1 (0.77) | TACR1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523305-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0566069-A1 | Tachykinin receptor antagonists, isoquinolones and their production | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-10-20 | — | — | EP | disclosed |