Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | THRA | P10827 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.30 |
| ▸ | CDK9 | P50750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936616 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8936639 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8936589 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8936611 | 0.99 | GABRA1 (0.36) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8936571 | 0.96 | CNR2 (0.36) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8937963 | 0.94 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8937949 | 0.94 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8937984 | 0.94 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8937990 | 0.94 | GABRA1 (0.35) | GABRA1GABRB2CNR2RARBCNR1 | |
| SCHEMBL8936540 | 0.93 | GABRA1 (0.39) | GABRA1GABRB2CNR2ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |