Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098233 | 0.79 | TP53 (0.53) | MEN1KMT2APOLBMAPTTHRB | |
| SCHEMBL8936588 | 0.72 | MAPT (0.50) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL18485389 | 0.69 | CA9 (0.49) | POLB | |
| SCHEMBL9099840 | 0.68 | MAPT (0.58) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL8936687 | 0.67 | NR1H2 (0.44) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL24001033 | 0.67 | MAPT (0.42) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL9101978 | 0.65 | MAPT (0.53) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL18613018 | 0.65 | SMN1; SMN2 (0.55) | MAPTLMNASMN1; SMN2GAA | |
| SCHEMBL9853429 | 0.64 | NR1H2 (0.47) | KMT2APOLBMAPTLMNASMN1; SMN2 | |
| SCHEMBL8936669 | 0.63 | TP53 (0.46) | MEN1KMT2APOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547951-A | ENZYME INHIBITORS; AIDS | BOEHRINGER INGELHEIM PHARAMCEUTICALS, INC. (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0417534-A1 | Pyrido[2,3-b][1,4]benzoxazepin (and thiazepin)-6(5H)-ones and thiones and their use in the prevention or treatment of AIDS | Boehringer Ingelheim Pharmaceuticals Inc. (US) | 1991-03-20 | — | — | EP | disclosed |