Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 2/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 2/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 2/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 2/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 2/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 2/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 2/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10714528 | 0.76 | KDM4E (0.39) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL27977561 | 0.76 | — | — | |
| SCHEMBL642416 | 0.76 | — | — | |
| SCHEMBL23518189 | 0.76 | KDM4E (0.36) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL12041542 | 0.73 | KDM4E (0.37) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL31122224 | 0.73 | POLB (0.38) | KDM4EALDH1A1SMN1; SMN2POLBNAPRT | |
| SCHEMBL8508786 | 0.72 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL10716939 | 0.71 | — | — | |
| SCHEMBL8351769 | 0.71 | HSP90AA1 (0.38) | KDM4EALDH1A1SMN1; SMN2POLBLMNA | |
| SCHEMBL1579715 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1042333-C | 5, 6-disubstituted-3-picolyl ammonium halide compound and preparation method thereof | AMERICAN CYANAMID CO (US) | 1999-03-03 | — | — | CN | disclosed |
| CN-1190094-A | Process of 5-(substituted methyl)-2,3-pyridinedicarboxylic acids | AMERICAN CYANAMID CO (US) | 1998-08-12 | — | — | CN | disclosed |
| US-5545835-A | CHEMICAL INTERMEDIATES FOR PREPARATION OF SUBSTITUTED 2,3-PYRIDINEDICARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1996-08-13 | — | — | US | disclosed |
| US-5378843-A | Halogenation, quaternization | AMERICAN CYANAMID COMPANY (US) | 1995-01-03 | — | — | US | disclosed |
| US-5288866-A | Chemical intermediates in the preparation of purity herbicides | AMERICAN CYANAMID COMPANY (US) | 1994-02-22 | — | — | US | disclosed |