Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.32 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10429997 | 0.79 | FYN (0.39) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL482581 | 0.75 | NPSR1 (0.46) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL30701742 | 0.71 | NPSR1 (0.50) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL896548 | 0.71 | NPSR1 (0.63) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL12095301 | 0.70 | KDM4E (0.53) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL7490024 | 0.69 | NPSR1 (0.54) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3558034 | 0.68 | NPSR1 (0.49) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL3817278 | 0.68 | GAA (0.65) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL14586465 | 0.68 | GAA (0.65) | NPSR1ATMMEN1KMT2AALDH1A1 | |
| SCHEMBL13049649 | 0.68 | GAA (0.65) | NPSR1ATMMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5576429-A | HUMAN T-CELL LEUKEMIA/LYMPHOMA VIRICIDE; ANTITUMOR AGENT | MEDIVIR AB (SE) | 1996-11-19 | — | — | US | disclosed |
| EP-0357571-B1 | Pyrimidine nucleosides | MEDIVIR AB (SE) | 1996-04-03 | — | — | EP | disclosed |
| EP-0691333-A2 | Pyrimidine derivatives, process for their preparation and their use as precursors | Medivir Aktiebolag (SE) | 1996-01-10 | — | — | EP | disclosed |
| US-5440040-A | Drug for Aids therapy; viricides | MEDIVIR AB (SE) | 1995-08-08 | — | — | US | disclosed |
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |
| WO-1989012061-A1 | PYRIMIDINE NUCLEOSIDES AND INTERMEDIATES | MEDIVIR AB (SE) | 1989-12-14 | — | — | WO | disclosed |