Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936693 | 0.79 | NPSR1 (0.56) | FYNGAANPSR1ATMMEN1 | |
| SCHEMBL17225264 | 0.74 | FYN (0.41) | FYNLPLLIPGMEN1KMT2A | |
| SCHEMBL29836817 | 0.70 | FYN (0.44) | FYNMEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL7191487 | 0.67 | LPL (0.46) | LPLLIPGALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14438064 | 0.67 | HPGDS (0.42) | FYNLPLLIPGMEN1KMT2A | |
| SCHEMBL21789413 | 0.66 | GAA (0.48) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL3822740 | 0.66 | GAA (0.48) | GAANPSR1ATMMEN1KMT2A | |
| SCHEMBL17225266 | 0.66 | FYN (0.38) | FYNLPLLIPGMEN1KMT2A | |
| SCHEMBL21965726 | 0.65 | CYP1A1 (0.33) | CYP1A2 | |
| SCHEMBL25097619 | 0.65 | GAA (0.47) | GAANPSR1ATMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0357571-A2 | Pyrimidine nucleosides | Medivir Aktiebolag (SE) | 1990-03-07 | — | — | EP | disclosed |