Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 7/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204708 | 0.89 | CYP19A1 (0.44) | CYP19A1CYP11B1SLC6A4HTR2AALDH1A1 | |
| SCHEMBL9201287 | 0.88 | CYP19A1 (0.39) | CYP19A1CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9202290 | 0.88 | CYP19A1 (0.39) | CYP19A1CYP11B1SLC6A4HTR2AKCNH2 | |
| SCHEMBL8936722 | 0.88 | CYP19A1 (0.46) | CYP19A1CYP11B1SLC6A4HTR2AKCNH2 | |
| SCHEMBL8936729 | 0.87 | CYP19A1 (0.41) | CYP19A1CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL9200301 | 0.86 | CYP19A1 (0.38) | CYP19A1CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8936774 | 0.85 | CYP19A1 (0.39) | CYP19A1CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8936761 | 0.85 | CYP19A1 (0.44) | CYP19A1CYP11B1SLC6A4HTR2AKCNH2 | |
| SCHEMBL8936685 | 0.85 | CYP19A1 (0.37) | CYP19A1CYP11B1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8936780 | 0.85 | KDM4E (0.38) | CYP19A1CYP11B1SLC6A4HTR2AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |