Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202290 | 0.89 | CYP19A1 (0.39) | CYP19A1CYP11B1KDM4E | |
| SCHEMBL9204708 | 0.88 | CYP19A1 (0.44) | CYP19A1CYP11B1KDM4EALDH1A1MAPT | |
| SCHEMBL9201287 | 0.87 | CYP19A1 (0.39) | CYP19A1CYP11B1KDM4EALDH1A1TSHR | |
| SCHEMBL9201316 | 0.87 | CYP19A1 (0.46) | CYP19A1CYP11B1 | |
| SCHEMBL8936722 | 0.87 | CYP19A1 (0.46) | CYP19A1CYP11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL8936723 | 0.87 | CYP19A1 (0.39) | CYP19A1CYP11B1KDM4EALDH1A1TSHR | |
| SCHEMBL9200301 | 0.85 | CYP19A1 (0.38) | CYP19A1CYP11B1KDM4EALDH1A1MAPT | |
| SCHEMBL8936761 | 0.84 | CYP19A1 (0.44) | CYP19A1CYP11B1 | |
| SCHEMBL8936780 | 0.84 | KDM4E (0.38) | CYP19A1CYP11B1KDM4E | |
| SCHEMBL8936774 | 0.84 | CYP19A1 (0.39) | CYP19A1CYP11B1KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |