Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.58 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19566595 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL17450350 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL28206179 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL4075410 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL16446324 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL15417618 | 0.79 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPT | |
| SCHEMBL940881 | 0.79 | CYP19A1 (0.62) | CYP19A1BRD4HSP90AA1KDM4E | |
| Hydrochloric Acid SCHEMBL11356117 | 0.77 | CYP19A1 (0.61) | CYP19A1BRD4HSP90AA1KDM4E | |
| SCHEMBL8936736 | 0.77 | CYP19A1 (0.53) | CYP19A1BRD4HSP90AA1CYP2C19KCNMA1 | |
| SCHEMBL9202589 | 0.77 | BRD4 (0.51) | CYP19A1BRD4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |