Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 8/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.49 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9202589 | 0.88 | BRD4 (0.51) | CYP19A1BRD4HTTMEN1KMT2A | |
| SCHEMBL9202210 | 0.81 | BRD4 (0.51) | CYP19A1BRD4HTTLMNAHSP90AA1 | |
| SCHEMBL3158915 | 0.81 | CYP19A1 (0.50) | CYP19A1BRD4HTTHPGDKMT2A | |
| SCHEMBL8936696 | 0.81 | BRD4 (0.51) | CYP19A1BRD4HIF1ACYP3A4SMN1; SMN2 | |
| SCHEMBL9202769 | 0.81 | BRD4 (0.51) | CYP19A1BRD4 | |
| SCHEMBL9747728 | 0.81 | CCR1 (0.55) | CYP19A1HTTMEN1LMNACYP3A4 | |
| SCHEMBL7445529 | 0.78 | CCR1 (0.50) | CYP19A1BRD4HTTMEN1LMNA | |
| SCHEMBL8936757 | 0.78 | BRD4 (0.48) | CYP19A1BRD4HSP90AA1CYP3A4ALOX15 | |
| SCHEMBL9197402 | 0.78 | CYP19A1 (0.56) | CYP19A1BRD4MEN1MAPTKMT2A | |
| SCHEMBL8936807 | 0.77 | CYP19A1 (0.58) | CYP19A1BRD4HSP90AA1MAPTKCNMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587392-A | THERAPY FOR ESTROGEN DEPENDENT DISEASES | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1996-12-24 | — | — | US | disclosed |
| EP-0684235-A1 | Novel azolyl methyl phenyl derivatives having aromatase inhibitory activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-29 | — | — | EP | disclosed |