Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936917 | 0.62 | TACR1 (1.00) | TACR1 | |
| SCHEMBL16664112 | 0.62 | NPC1 (0.56) | CHRNB2CHRNA4LMNA | |
| SCHEMBL7668214 | 0.60 | TSHR (0.52) | TACR1LMNA | |
| SCHEMBL16663928 | 0.59 | CA1 (0.49) | LMNA | |
| SCHEMBL12474423 | 0.58 | DAO (0.73) | LMNA | |
| SCHEMBL29125822 | 0.58 | RAB9A (0.54) | — | |
| SCHEMBL16663991 | 0.58 | CA1 (0.49) | LMNA | |
| SCHEMBL16664061 | 0.58 | CA1 (0.49) | LMNA | |
| SCHEMBL16664057 | 0.58 | CA1 (0.49) | LMNA | |
| SCHEMBL29125683 | 0.57 | TSHR (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494926-A | ANTIINFLAMMATORY AGENT, ANTIARTHRITIC AGENT; TREATING PAIN, HEADACHE | MERCK SHARP & DOHME LTD. (GB) | 1996-02-27 | — | — | US | disclosed |
| WO-1993024465-A1 | 2/3-(HETEROCYCLIC ALKYL AMINO)-1-(SUBST.-PHENYL-METHOXY)-ETHANES/PROPANES AS TACHYKININ-RECEPTOR ANTAGONISTS | MERCK SHARP & DOHME LIMITED (GB) | 1993-12-09 | — | — | WO | disclosed |