Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 5/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 3/20 | 0.44 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | NMUR2 | Q9GZQ4 | 3/20 | 0.44 |
| ▸ | NTSR2 | O95665 | 2/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.44 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.44 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | CTSE | P14091 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31410876 | 0.89 | CALCRL (0.49) | CAPN1KEAP1CTSDBACE1NTSR2 | |
| SCHEMBL30532203 | 0.88 | CALCRL (0.45) | CAPN1KEAP1CTSDBACE1NTSR2 | |
| SCHEMBL29983307 | 0.88 | ACE (0.44) | CAPN1NMUR2NTSR2NTSR1 | |
| SCHEMBL30072960 | 0.87 | CAPN1 (0.48) | STAT3CAPN1NTSR2NTSR1 | |
| SCHEMBL30434738 | 0.86 | NTSR2 (0.46) | CAPN1NMUR2NTSR2NTSR1 | |
| SCHEMBL29641778 | 0.85 | XIAP (0.47) | STAT3NTSR2NTSR1CALCRL | |
| SCHEMBL30401176 | 0.85 | SLC6A2 (0.49) | CAPN1NTSR2NTSR1CALCRL | |
| SCHEMBL30444754 | 0.85 | GRB2 (0.44) | STAT3CAPN1CTSDBACE1NMUR2 | |
| SCHEMBL31183007 | 0.85 | CAPN1 (0.51) | STAT3CAPN1KEAP1CTSDBACE1 | |
| SCHEMBL30853505 | 0.84 | GRB2 (0.55) | STAT3CAPN1CTSDBACE1NMUR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |
| EP-0366728-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY. | UNIV MINNESOTA (US) | 1990-05-09 | — | — | EP | disclosed |
| WO-1989001942-A1 | POLYPEPTIDES WITH FIBRONECTIN ACTIVITY | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1989-03-09 | — | — | WO | disclosed |