Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 2/20 | 0.49 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30832636 | 0.93 | ACE (0.53) | OPRD1CASP1CTSDACEMME | |
| SCHEMBL29352065 | 0.90 | ACE (0.58) | OPRD1CTSDACEMMECPA1 | |
| SCHEMBL30565308 | 0.89 | ACE (0.57) | OPRD1CTSDACEMMECPA1 | |
| SCHEMBL30746956 | 0.86 | ACE (0.64) | ACEMMECPA1ACE2ANPEP | |
| SCHEMBL31089980 | 0.84 | ACE (0.67) | ACEMMECPA1ACE2 | |
| SCHEMBL30900763 | 0.84 | ACE (0.60) | OPRD1ACEMMECPA1ACE2 | |
| SCHEMBL30405655 | 0.84 | ACE (0.50) | OPRD1CASP1ACEMMECPA1 | |
| SCHEMBL30974102 | 0.84 | BACE1 (0.54) | OPRD1CASP1BACE1BACE2OPRM1 | |
| SCHEMBL31721019 | 0.83 | ACE (0.50) | OPRD1CTSDACEMMECPA1 | |
| SCHEMBL29608723 | 0.83 | CTSD (0.51) | OPRD1CTSDACEMMECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |