Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM5A | P29375 | 1/20 | 0.42 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.42 |
| ▸ | REN | P00797 | 6/20 | 0.41 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.41 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.39 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936988 | 1.00 | KDM1A (0.44) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL10336152 | 0.99 | KDM1A (0.45) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL10336157 | 0.99 | KDM1A (0.45) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL6384984 | 0.86 | MAPK8 (0.41) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL6384987 | 0.86 | MAPK8 (0.41) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL30666383 | 0.86 | KDM1A (0.55) | KDM1AMAPK8MAPK9MAPK10MAOB | |
| SCHEMBL38655084 | 0.85 | BDKRB2 (0.43) | KDM1AMAPK8MAPK9MAPK10EPHA2 | |
| SCHEMBL30925880 | 0.85 | MAPK8 (0.47) | KDM1AMAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL30925881 | 0.85 | MAPK8 (0.47) | KDM1AMAPK8MAPK9MAPK10NMUR2 | |
| SCHEMBL8937029 | 0.85 | EPHA2 (0.45) | EPHA2NMUR2NMUR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |