Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT2 | O60551 | 1/20 | 0.43 |
| ▸ | NMT1 | P30419 | 1/20 | 0.43 |
| ▸ | FURIN | P09958 | 5/20 | 0.43 |
| ▸ | NPY4R | P50391 | 7/20 | 0.41 |
| ▸ | NPY1R | P25929 | 4/20 | 0.41 |
| ▸ | NPY2R | P49146 | 4/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.41 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937002 | 1.00 | NMT2 (0.43) | NMT2NMT1FURINNPY4RNPY1R | |
| SCHEMBL31085370 | 0.90 | NPY4R (0.50) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30423518 | 0.89 | NPY4R (0.50) | NMT2NMT1FURINNPY4RNPY1R | |
| SCHEMBL30373028 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL30372694 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL31106970 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL29461533 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL5598706 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL31717990 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R | |
| SCHEMBL30713830 | 0.88 | SLC15A2 (0.51) | NMT2NMT1NPY4RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |