Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.45 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.42 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.42 |
| ▸ | GRB2 | P62993 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 7/20 | 0.41 |
| ▸ | NPY4R | P50391 | 7/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 7/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.40 |
| ▸ | CALCR | P30988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937029 | 1.00 | EPHA2 (0.45) | EPHA2NMUR2NMUR1GRB2NPY2R | |
| SCHEMBL30523349 | 0.89 | EPHA2 (0.42) | EPHA2NMUR2NMUR1GRB2NPY2R | |
| SCHEMBL30367979 | 0.87 | EPHA2 (0.42) | EPHA2NMUR2NMUR1NPY2RNPY4R | |
| SCHEMBL31487371 | 0.86 | GRB2 (0.53) | EPHA2NMUR2NMUR1GRB2NPY1R | |
| SCHEMBL10336152 | 0.86 | KDM1A (0.45) | EPHA2NMUR2NMUR1 | |
| SCHEMBL10336157 | 0.86 | KDM1A (0.45) | EPHA2NMUR2NMUR1 | |
| SCHEMBL8936994 | 0.85 | KDM1A (0.44) | EPHA2NMUR2NMUR1 | |
| SCHEMBL8936988 | 0.85 | KDM1A (0.44) | EPHA2NMUR2NMUR1 | |
| SCHEMBL30988896 | 0.84 | EPHA2 (0.48) | EPHA2XIAPRAMP3CALCR | |
| SCHEMBL30198799 | 0.84 | GRB2 (0.48) | EPHA2NMUR2NMUR1GRB2XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673384-A4 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS. | UNIV MINNESOTA (US) | 1996-10-09 | — | — | EP | claimed |
| EP-0673384-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | THE REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1995-09-27 | — | — | EP | claimed |
| WO-1994013692-A1 | POLYPEPTIDES USEFUL FOR TREATING INFLAMMATORY DISORDERS | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1994-06-23 | — | — | WO | claimed |