Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 5/20 | 0.63 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.63 |
| ▸ | CDK2 | P24941 | 4/20 | 0.61 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.61 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.61 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.56 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 5/20 | 0.52 |
| ▸ | CDC7 | O00311 | 3/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 6-(Decyloxy)Purine SCHEMBL6234483 | 1.00 | CDK1 (0.63) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL7027159 | 1.00 | CDK1 (0.63) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL5175462 | 1.00 | CDK1 (0.63) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL9197744 | 0.94 | PDPK1 (0.62) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL9094494 | 0.89 | PDPK1 (0.64) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL3388864 | 0.82 | PDPK1 (0.68) | CDK1CDK2PDPK1PAK1HTT | |
| SCHEMBL27323757 | 0.81 | PDPK1 (0.67) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL4419598 | 0.76 | PAK1 (0.60) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL5175458 | 0.75 | CDK1 (0.49) | CDK1CCNB1CDK2CCNA2CCNA1 | |
| SCHEMBL8937059 | 0.75 | CDK1 (0.49) | CDK1CCNB1CDK2CCNA2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580973-A | Process for preparing optically active nucleosides from chiral cyclobutanones | LEE-RUFF, EDWARD | 1996-12-03 | — | — | US | disclosed |