SCHEMBL9094494

SCHEMBL9094494

CCCOc1ncnc2nc[nH]c12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDPK1 O15530 2/20 0.64
CDK1 P06493 5/20 0.60
CDK2 P24941 5/20 0.60
CCNB1 P14635 4/20 0.60
CCNA2 P20248 3/20 0.60
CCNA1 P78396 3/20 0.60
CDC7 O00311 3/20 0.56
DBF4 Q9UBU7 3/20 0.56
LMNA P02545 4/20 0.52
HTT P42858 5/20 0.51
MAP3K5 Q99683 1/20 0.51
PIN1 Q13526 1/20 0.51
BRD4 O60885 1/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
PAK1 Q13153 1/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
LRRK2 Q5S007 2/20 0.46
CHEK1 O14757 1/20 0.46
AURKA O14965 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9197744 0.92 PDPK1 (0.62) PDPK1CDK1CDK2CCNB1CCNA2
SCHEMBL5175462 0.89 CDK1 (0.63) PDPK1CDK1CDK2CCNB1CCNA2
SCHEMBL7027159 0.89 CDK1 (0.63) PDPK1CDK1CDK2CCNB1CCNA2
SCHEMBL8937061 0.89 CDK1 (0.63) PDPK1CDK1CDK2CCNB1CCNA2
6-(Decyloxy)Purine SCHEMBL6234483 0.89 CDK1 (0.63) PDPK1CDK1CDK2CCNB1CCNA2
SCHEMBL3388864 0.86 PDPK1 (0.68) PDPK1CDK1CDK2CDC7DBF4
SCHEMBL27323757 0.85 PDPK1 (0.67) PDPK1CDK1CDK2CCNB1CCNA2
SCHEMBL284830 0.78 PDPK1 (1.00) PDPK1CDK1CDK2CDC7DBF4
Water SCHEMBL6474310 0.77 PDPK1 (0.96) PDPK1CDK1CDK2CDC7DBF4
SCHEMBL6267606 0.76 CDC7 (0.74) PDPK1CDK1CDK2CCNB1CCNA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2129126-A None JP disclosed
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 US disclosed
US-20200232005-A1 Methods of Producing and Using Single-Stranded Deoxyribonucleic Acids and Compositions for Use in Practicing the Same TAKARA BIO USA, INC. 2020-07-23 US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 US disclosed
EP-3283638-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2018-02-21 EP disclosed
EP-0504279-A4 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES 1993-02-17 EP disclosed
US-5185437-A 6-substituted 2',3'-dideoxypurine nucleosides; treatment for human immunodeficiency virus and heptatis b virus BURROUGHS WELLCOME CO. (US) 1993-02-09 US disclosed
EP-0504279-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES. CHEMGEN CORP (US) 1992-09-23 EP disclosed
US-5068320-A 2-amino-6-(cyclopropylamino)purine-9-β-D-2',3'-dideoxyribofuranoside and its pharmaceutically acceptable salts BURROUGHS WELLCOME CO. (US) 1991-11-26 US disclosed
WO-1991009130-A1 FERMENTATION PROCESS FOR THE PRODUCTION OF PYRIMIDINE DEOXYRIBONUCLEOSIDES CHEMGEN CORPORATION (US) 1991-06-27 WO disclosed
EP-0421819-A1 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1991-04-10 EP disclosed
JP-H02129126-A NUCLEOSIDE FOR CURING WELLCOME FOUND LTD:THE 1990-05-17 JP disclosed
EP-0366287-A1 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1990-05-02 EP disclosed
EP-0294114-A2 Antiviral compounds THE WELLCOME FOUNDATION LIMITED (GB) 1988-12-07 EP disclosed
EP-0286425-A2 Therapeutic nucleosides THE WELLCOME FOUNDATION LIMITED (GB) 1988-10-12 EP disclosed