Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 11/20 | 0.35 |
| ▸ | HTR2B | P41595 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 7/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938618 | 0.93 | HTR2C (0.36) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL8938943 | 0.91 | HTR2C (0.38) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL8937173 | 0.90 | ALOX5AP (0.31) | — | |
| SCHEMBL8937164 | 0.90 | ALOX5AP (0.31) | — | |
| SCHEMBL8936642 | 0.90 | HTR2C (0.34) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL13000904 | 0.90 | HTR2C (0.33) | HTR2CHTR2BHTR2A | |
| SCHEMBL8937167 | 0.89 | — | — | |
| SCHEMBL10163944 | 0.89 | NAAA (0.35) | — | |
| SCHEMBL8936809 | 0.87 | HTR2C (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL8936073 | 0.87 | HTR2C (0.33) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |