Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.69 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GPR183 | P32249 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.47 |
| ▸ | TUBB | P07437 | 1/20 | 0.47 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.47 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.47 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.47 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.47 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.47 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937435 | 1.00 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1CYP1A2POLBLMNA | |
| SCHEMBL8937620 | 0.93 | ALDH1A1 (0.79) | ALDH1A1L3MBTL1CYP1A2POLBLMNA | |
| SCHEMBL8937594 | 0.93 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1CYP1A2POLBLMNA | |
| SCHEMBL8937657 | 0.93 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1CYP1A2POLBLMNA | |
| SCHEMBL8937600 | 0.93 | ALDH1A1 (0.62) | ALDH1A1L3MBTL1CYP1A2POLBLMNA | |
| SCHEMBL8937251 | 0.89 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1CYP1A2POLBGPR183 | |
| SCHEMBL8937244 | 0.89 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1CYP1A2POLBGPR183 | |
| SCHEMBL8937249 | 0.89 | ALDH1A1 (0.72) | ALDH1A1L3MBTL1CYP1A2POLBGPR183 | |
| SCHEMBL8937224 | 0.88 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1CYP1A2POLBGPR183 | |
| SCHEMBL8937483 | 0.88 | ALDH1A1 (0.67) | ALDH1A1L3MBTL1CYP1A2POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559109-A | Method of treating a PAF-mediated pathology or for treating or preventing psoriasis, nephritis, asthma or shock by administering a PAF antagonist | SANKKO COMPANY, LIMITED (JP) | 1996-09-24 | — | — | US | claimed |
| US-5559109-A | Method of treating a PAF-mediated pathology or for treating or preventing psoriasis, nephritis, asthma or shock by administering a PAF antagonist | SANKKO COMPANY, LIMITED (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5192766-A | Platelet activating factor antagonist | SANKYO COMPANY, LIMITED (JP) | 1993-03-09 | — | — | US | disclosed |