Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | GPR183 | P32249 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8937586 | 1.00 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937589 | 1.00 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937498 | 0.93 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937637 | 0.93 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937500 | 0.93 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937674 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937478 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937669 | 0.89 | ALDH1A1 (0.52) | ALDH1A1L3MBTL1CYP1A2ABL1BCR | |
| SCHEMBL8937496 | 0.85 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CYP1A2KMT2AGPR183 | |
| SCHEMBL8937494 | 0.85 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1CYP1A2KMT2AGPR183 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559109-A | Method of treating a PAF-mediated pathology or for treating or preventing psoriasis, nephritis, asthma or shock by administering a PAF antagonist | SANKKO COMPANY, LIMITED (JP) | 1996-09-24 | — | — | US | disclosed |
| US-5556852-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | SANKYO COMPANY, LIMITED (JP) | 1996-09-17 | — | — | US | disclosed |
| US-5369106-A | N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists | SANKYO COMPANY, LIMITED (JP) | 1994-11-29 | — | — | US | disclosed |
| US-5192766-A | Platelet activating factor antagonist | SANKYO COMPANY, LIMITED (JP) | 1993-03-09 | — | — | US | disclosed |