SCHEMBL8937726

SCHEMBL8937726

NCCCCCCCCCCCC=Cc1ccccc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.43
CA2 P00918 6/20 0.42
CA12 O43570 5/20 0.42
CA9 Q16790 4/20 0.42
NFKB1 P19838 2/20 0.42
CDK4 P11802 1/20 0.42
CCND1 P24385 1/20 0.42
JUN P05412 1/20 0.42
NFE2L2 Q16236 1/20 0.42
CA1 P00915 1/20 0.41
CA4 P22748 1/20 0.41
TAAR1 Q96RJ0 1/20 0.40
LMNA P02545 1/20 0.40
MAPT P10636 1/20 0.40
TRIM24 O15164 1/20 0.38
TRIM33 Q9UPN9 1/20 0.38
KDM4E B2RXH2 1/20 0.38
BCHE P06276 1/20 0.38
GUSB P08236 1/20 0.38
CYSLTR2 Q9NS75 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL348173 0.93 TRPA1 (0.46) TRPA1CA2CA12CA9NFKB1
SCHEMBL347703 0.85 TRPA1 (0.48) TRPA1CA2CA12CA9NFKB1
SCHEMBL1277029 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL10750148 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL1072894 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL1001649 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL1072895 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL1001648 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL10743923 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2
SCHEMBL10752074 0.83 CYSLTR2 (0.50) TRPA1LMNAMAPTKDM4ECYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5534039-A POLLUTION CONTROL FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-07-09 US disclosed
EP-0539576-B1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME LUBRIZOL CORP (US) 1996-05-29 EP disclosed
US-5518510-A EXHAUST SYSTEMS WITH TRAPS FOR DIESEL ENGINES THE LUBRIZOL CORPORATION (US) 1996-05-21 US disclosed
US-5376154-A For diesel engines equipped with an exhaust system particulate trap; lowers ignition temperature of those particles THE LUBRIZOL CORPORATION (US) 1994-12-27 US disclosed
US-5344467-A Fuel additives THE LUBRIZOL CORPORATION (US) 1994-09-06 US disclosed
US-5340369-A To lower ignition temperature of particles collected in exhaust system trap THE LUBRIZOL CORPORATION (US) 1994-08-23 US disclosed
EP-0539572-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES The Lubrizol Corporation (US) 1993-05-05 EP disclosed
EP-0539579-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES The Lubrizol Corporation (US) 1993-05-05 EP disclosed
EP-0539576-A1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME. LUBRIZOL CORP (US) 1993-05-05 EP disclosed
WO-1992020765-A1 DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020763-A1 LOW-SULFUR DIESEL FUELS CONTAINING ORGANOMETALLIC COMPLEXES THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed
WO-1992020762-A1 ORGANOMETALLIC COMPLEX-ANTIOXIDANT COMBINATIONS, AND CONCENTRATES AND DIESEL FUELS CONTAINING SAME THE LUBRIZOL CORPORATION (US) 1992-11-26 WO disclosed