Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 4/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8938043 | 0.86 | ACP3 (0.54) | ACP3CYP1A2CYP2C19ALDH1A1MEN1 | |
| SCHEMBL7295893 | 0.80 | ACP3 (0.47) | ACP3CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL1773883 | 0.76 | ACP3 (0.57) | ACP3CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL7297203 | 0.76 | ACP3 (0.43) | ACP3KMT2AFFAR1AKR1B1PARP10 | |
| SCHEMBL8167782 | 0.72 | ACP3 (0.61) | ACP3CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL27042407 | 0.71 | ACP3 (0.51) | ACP3CYP1A2CYP2C19CYP2C9KDM4E | |
| SCHEMBL2303485 | 0.68 | GPR84 (0.54) | ACP3CYP1A2CYP2C19CYP2C9ALDH1A1 | |
| SCHEMBL6131123 | 0.68 | MAPT (0.58) | CYP1A2CYP2C19CYP2C9ALDH1A1MEN1 | |
| SCHEMBL17333287 | 0.67 | ACP3 (0.53) | ACP3CYP1A2CYP2C19CYP2C9MEN1 | |
| SCHEMBL21296202 | 0.67 | MC5R (0.67) | CYP1A2CYP2C19ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |