Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 12/20 | 1.00 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.41 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TDO2 | P48775 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11089244 | 0.77 | ACP3 (0.63) | ACP3CNR2 | |
| SCHEMBL777888 | 0.77 | ACP3 (0.64) | ACP3SRCIDO1TDO2 | |
| SCHEMBL232244 | 0.75 | ACP3 (0.79) | ACP3SRC | |
| SCHEMBL20588340 | 0.75 | ACP3 (0.66) | ACP3SRC | |
| SCHEMBL3884830 | 0.74 | ACP3 (1.00) | ACP3SRC | |
| Hydrochloric Acid SCHEMBL1133241 | 0.73 | ACP3 (0.76) | ACP3SRC | |
| SCHEMBL3289370 | 0.73 | ACP3 (0.57) | ACP3CNR2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL3294921 | 0.73 | ACP3 (0.57) | ACP3CNR2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL30986703 | 0.73 | ACP3 (0.57) | ACP3CNR2CACNA2D1CACNA1BCACNB1 | |
| SCHEMBL2390807 | 0.72 | ACP3 (0.56) | ACP3CNR2CACNA2D1CACNA1BCACNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5508273-A | ARALKYLPHOSPHONATES FOR OSTEOPOROSIS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |