Hydrochloric Acid

Hydrochloric Acid

SCHEMBL1133241

Cl.Cl.O=P(O)(O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.76

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SRC known ✓ P12931 1/20 0.62
▸ ACP3 P15309 17/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL232244 0.97 ACP3 (0.79) ACP3SRC
Phenol SCHEMBL4616870 0.89 ACP3 (0.68) ACP3SRC
SCHEMBL7228258 0.85 ACP3 (0.69) ACP3SRC
SCHEMBL16859931 0.85 ACP3 (0.71) ACP3SRC
Benzylphosphonic Acid SCHEMBL27465782 0.83 ACP3 (0.61) ACP3SRC
SCHEMBL8158042 0.82 ACP3 (0.65) ACP3SRC
SCHEMBL8158040 0.82 ACP3 (0.65) ACP3SRC
SCHEMBL20588340 0.79 ACP3 (0.66) ACP3SRC
SCHEMBL777888 0.78 ACP3 (0.64) ACP3SRC
SCHEMBL3884830 0.78 ACP3 (1.00) ACP3SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117843684-A Organic phosphorus compound, flame retardant and flame retardant product formed by same 帝人株式会社 2024-04-09 — — CN disclosed
US-10919923-B2 Organic phosphorus-based compound, and flame retardant and flame-retardant product comprising the same TEIJIN LIMITED (JP) 2021-02-16 — — US disclosed
EP-3514161-B1 ORGANOPHOSPHORUS COMPOUND, FLAME RETARDANT, AND FLAME-RETARDANT PRODUCT INCLUDING SAME TEIJIN LTD (JP) 2020-05-13 — — EP disclosed
WO-2020009076-A1 POLYCARBONATE RESIN COMPOSITION 帝人株式会社 2020-01-09 — — WO disclosed
EP-3514161-A1 ORGANOPHOSPHORUS COMPOUND, FLAME RETARDANT, AND FLAME-RETARDANT PRODUCT INCLUDING SAME Teijin Limited (JP) 2019-07-24 — — EP disclosed
US-20190218237-A1 ORGANIC PHOSPHORUS-BASED COMPOUND, AND FLAME RETARDANT AND FLAME-RETARDANT PRODUCT COMPRISING THE SAME TEIJIN LIMITED (JP) 2019-07-18 — — US disclosed
EP-2511338-B1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED PRODUCTS THEREOF TEIJIN LTD (JP) 2016-04-27 — — EP disclosed
EP-2287253-B1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDING DERIVED THEREFROM TEIJIN CHEMICALS LTD (JP) 2016-01-06 — — EP disclosed
US-8859655-B2 Flame retardant resin composition and molded article thereof TEIJIN CHEMICALS, LTD. (JP) 2014-10-14 — — US disclosed
US-8618196-B2 Flame retardant resin composition and molded article thereof TEIJIN LIMITED (JP) 2013-12-31 — — US disclosed
EP-2399959-A1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF Teijin Chemicals, Ltd. (JP) 2011-12-28 — — EP disclosed
US-20110301266-A1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2011-12-08 — — US disclosed
US-20110092623-A1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREOF TEIJIN CHEMICALS, LTD. (JP) 2011-04-21 — — US disclosed
EP-2287253-A1 FLAME-RETARDANT RESIN COMPOSITION AND MOLDING DERIVED THEREFROM Teijin Chemicals, Ltd. (JP) 2011-02-23 — — EP disclosed
US-7786197-B2 Flame retardant resin composition and molded articles thereof TEIJIN CHEMICALS, LTD. (JP) 2010-08-31 — — US disclosed
EP-1408085-B1 FLAME RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREFROM TEIJIN CHEMICALS LTD (JP) 2008-06-18 — — EP disclosed
US-7087667-B2 Flame-retardant resin composition and molded article therefrom TEIJIN CHEMICALS, LTD. (JP) 2006-08-08 — — US disclosed
US-20050256293-A1 Flame retardant resin composition and molded articles thereof TEIJIN CHEMICALS LTD. (JP) 2005-11-17 — — US disclosed
US-20040127611-A1 Flame-retardant resin composition and molded article therefrom TEIJIN CHEMICALS LTD. (JP) 2004-07-01 — — US disclosed
EP-1408085-A1 FLAME;RETARDANT RESIN COMPOSITION AND MOLDED ARTICLE THEREFROM Teijin Chemicals, Ltd. (JP) 2004-04-14 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10919923-B2 Organic phosphorus-based compound, and flame retardant and flame-retardant product comprising the same PF4, TPD52L2, AFF4 SRC 3188/4885ACP3 362/4885
US-20190218237-A1 ORGANIC PHOSPHORUS-BASED COMPOUND, AND FLAME RETARDANT AND FLAME-RETARDANT PRODUCT COMPRISING THE SAME PF4, TPD52L2, AFF4 SRC 3188/4885ACP3 362/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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