Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.55 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.55 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.55 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.52 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4943394 | 0.88 | MAPT (0.60) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL30819288 | 0.85 | L3MBTL1 (0.68) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL4940856 | 0.85 | L3MBTL1 (0.68) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14247580 | 0.85 | MAPK1 (0.60) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27539926 | 0.85 | MAPK1 (0.64) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11901762 | 0.82 | TDP1 (0.54) | MAPK1MAPTALDH1A1L3MBTL1TDP1 | |
| SCHEMBL2506788 | 0.81 | KMT2A (0.45) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9116525 | 0.81 | MAPT (0.62) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL11901725 | 0.78 | MEN1 (0.62) | MAPTMEN1KMT2AAKR1B10AKR1B1 | |
| SCHEMBL8955420 | 0.78 | MAPT (0.58) | MAPK1MAPTALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018013430-A2 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2018-01-18 | — | — | WO | disclosed |
| US-5484762-A | Aryloxy-n-(substituted phenyl) benzotriazole herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1996-01-16 | — | — | US | disclosed |