Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 11/20 | 0.45 |
| ▸ | MAOA | P21397 | 9/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8935962 | 0.93 | MAP2K1 (0.49) | MAP2K1MAOBMAOAACHESIGMAR1 | |
| SCHEMBL8935983 | 0.89 | MAP2K1 (0.52) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8935883 | 0.86 | MAP2K1 (0.52) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8938922 | 0.85 | MAP2K1 (0.55) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8935808 | 0.84 | MAOB (0.59) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8935814 | 0.83 | MAOA (0.59) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8938954 | 0.82 | ROCK1 (0.46) | — | |
| SCHEMBL8935917 | 0.81 | MAP2K1 (0.55) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8935887 | 0.81 | MAP2K1 (0.55) | MAP2K1MAOBMAOAACHE | |
| SCHEMBL8938927 | 0.80 | MAOB (0.52) | MAP2K1MAOBMAOAACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188117-B2 | Piperidinyl-substituted isoquinolone derivatives | SANOFI-AVENTIS (FR) | 2012-05-29 | — | — | US | disclosed |