SCHEMBL8939138

SCHEMBL8939138

CC(CO)c1ccccc1.[NaH]

nearest known ligand 0.65

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 6/20 0.65
TAAR1 Q96RJ0 3/20 0.56
AOC3 Q16853 2/20 0.50
RIPK1 Q13546 1/20 0.48
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.44
ADRA2A P08913 1/20 0.43
ADRA2C P18825 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL60429 0.97 TRPA1 (0.68) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL1260 0.97 TRPA1 (0.68) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL61000 0.97 TRPA1 (0.68) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL8976575 0.95 TRPA1 (0.65) TRPA1TAAR1AOC3RIPK1KDM4E
Hydrochloric Acid SCHEMBL28757862 0.95 TRPA1 (0.65) TRPA1TAAR1AOC3RIPK1KDM4E
Ammonia Solution, Strong SCHEMBL28122152 0.95 TRPA1 (0.65) TRPA1TAAR1AOC3RIPK1KDM4E
Methane SCHEMBL27517092 0.95 TRPA1 (0.65) TRPA1TAAR1AOC3RIPK1KDM4E
Methylamine SCHEMBL10944526 0.91 TRPA1 (0.61) TRPA1TAAR1AOC3RIPK1KDM4E
SCHEMBL28632394 0.89 TRPA1 (0.59) TRPA1TAAR1AOC3RIPK1KDM4E
Acetic Acid SCHEMBL6330530 0.89 TRPA1 (0.59) TRPA1TAAR1AOC3RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5508310-A ADMINISTERING SUBSTITUTED ALDEHYDES OR KETONES WHICH CAN REACT WITH T-CELL SURFACE GROUPS TO FORM SCHIFF BASES BURROUGHS WELLCOME CO. (US) 1996-04-16 US disclosed