Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610258 | 0.80 | — | — | |
| SCHEMBL368314 | 0.73 | SLC1A3 (0.37) | SLC1A3SLC1A2SLC1A1ALDH1A1TSHR | |
| SCHEMBL4610817 | 0.69 | CA1 (0.38) | — | |
| SCHEMBL540008 | 0.69 | TRPA1 (0.37) | ALDH1A1TSHRTRPA1 | |
| SCHEMBL28326453 | 0.69 | CA1 (0.40) | SLC1A3SLC1A2SLC1A1ALDH1A1 | |
| SCHEMBL4575363 | 0.69 | CHRM1 (0.42) | SLC1A3SLC1A2SLC1A1TSHR | |
| SCHEMBL3714069 | 0.67 | ZDHHC7 (0.38) | ALDH1A1TSHRTRPA1 | |
| SCHEMBL15065505 | 0.67 | — | — | |
| SCHEMBL28776363 | 0.65 | — | — | |
| SCHEMBL11469416 | 0.65 | TRPA1 (0.35) | SLC1A3SLC1A2SLC1A1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102791713-B | Imidazo [1,2-A ] pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases | JANSSEN PHARMACEUTICA N.V. (BE) | 2016-02-03 | — | — | CN | disclosed |
| CN-102791713-A | Imidazo [1,2-A ] pyrazine derivatives and their use for the prevention or treatment of neurological, psychiatric and metabolic disorders and diseases | JANSSEN PHARMACEUTICA NV | 2012-11-21 | — | — | CN | disclosed |
| CN-1946703-A | Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators | TRANSTECH PHARMA INC (US) | 2007-04-11 | — | — | CN | disclosed |
| US-5532228-A | ANTITUMOR, PSORIASIS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |