Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939171 | 0.83 | KCNN4 (0.47) | KCNN4OPRM1GRIN2DGRIN1GRIN2A | |
| SCHEMBL13828216 | 0.74 | OPRM1 (0.55) | KCNN4OPRM1GRIN2DGRIN1GRIN2A | |
| SCHEMBL12241772 | 0.74 | NPC1 (0.49) | HIF1ANPSR1MEN1LMNAKMT2A | |
| SCHEMBL8880188 | 0.70 | OPRM1 (0.41) | KCNN4OPRM1GRIN2DGRIN1GRIN2A | |
| SCHEMBL8939190 | 0.70 | KCNN4 (0.44) | KCNN4OPRM1GRIN2DGRIN1GRIN2A | |
| SCHEMBL8939167 | 0.69 | KCNN4 (0.47) | KCNN4OPRM1GRIN2DGRIN1GRIN2A | |
| SCHEMBL5447551 | 0.68 | KCNN4 (0.41) | KCNN4CYP2C19HIF1AKIF11MEN1 | |
| SCHEMBL3729769 | 0.68 | CYP2C19 (0.42) | KCNN4KCNH2CYP2C19HIF1AKIF11 | |
| SCHEMBL8939158 | 0.68 | KCNN4 (0.48) | KCNN4OPRM1DRD3DRD2CYP2C19 | |
| SCHEMBL8939163 | 0.67 | KCNN4 (0.44) | KCNN4OPRM1GRIN2DGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532228-A | ANTITUMOR, PSORIASIS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |