Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SENP1 | Q9P0U3 | 3/20 | 0.79 |
| ▸ | CCKBR | P32239 | 8/20 | 0.64 |
| ▸ | BRD4 | O60885 | 6/20 | 0.62 |
| ▸ | BRD2 | P25440 | 6/20 | 0.62 |
| ▸ | BRD3 | Q15059 | 6/20 | 0.62 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.60 |
| ▸ | CCKAR | P32238 | 2/20 | 0.59 |
| ▸ | OXTR | P30559 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8711261 | 1.00 | SENP1 (0.79) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL8711263 | 1.00 | SENP1 (0.79) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9865718 | 0.92 | SENP1 (0.76) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL4413832 | 0.91 | SENP1 (0.75) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL8939498 | 0.90 | SENP1 (0.73) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL1574634 | 0.90 | SENP1 (0.73) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL1574343 | 0.90 | SENP1 (0.75) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL1574340 | 0.90 | SENP1 (0.75) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL9868905 | 0.90 | SENP1 (0.73) | SENP1CCKBRBRD4BRD2BRD3 | |
| SCHEMBL6940307 | 0.90 | SENP1 (0.73) | SENP1CCKBRBRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5580979-A | Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions | TRUSTEES OF TUFTS UNIVERSITY (US) | 1996-12-03 | — | — | US | disclosed |