Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 17/20 | 0.64 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4023040 | 0.87 | AR (0.75) | ARPGRHDAC1 | |
| SCHEMBL8939711 | 0.86 | AR (0.59) | ARPGR | |
| SCHEMBL8939558 | 0.86 | AR (0.77) | ARPGRHDAC1 | |
| SCHEMBL8939682 | 0.84 | AR (0.61) | ARHDAC1 | |
| SCHEMBL7756025 | 0.83 | AR (0.60) | ARPGRHDAC1 | |
| SCHEMBL8939586 | 0.83 | AR (0.60) | AR | |
| SCHEMBL4031610 | 0.81 | AR (0.80) | ARPGRHDAC1 | |
| SCHEMBL1715935 | 0.79 | AR (0.64) | ARPGRHDAC1 | |
| SCHEMBL4025432 | 0.78 | AR (0.59) | AR | |
| SCHEMBL4025434 | 0.78 | AR (0.60) | ARHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5589497-A | ANTIANDROGENS | Uclaf, Roussel (FR) | 1996-12-31 | — | — | US | disclosed |
| US-5556983-A | ANTIANDROGENS | ROUSSEL UCLAF (FR) | 1996-09-17 | — | — | US | disclosed |
| US-5434176-A | Antiandrogens | ROUSSEL UCLAF (FR) | 1995-07-18 | — | — | US | disclosed |
| EP-0578516-A1 | Optionally substituted phenylimidazolidins, process for their preparation, their use as medicaments and the pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1994-01-12 | — | — | EP | disclosed |