Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.37 |
| ▸ | NMUR1 | Q9HB89 | 2/20 | 0.37 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6976859 | 0.94 | F2 (0.39) | F2 | |
| SCHEMBL8939663 | 0.94 | F2 (0.39) | F2 | |
| SCHEMBL7506385 | 0.94 | F2 (0.40) | F2NMUR2NMUR1EPHA2 | |
| SCHEMBL2526255 | 0.94 | F2 (0.46) | F2 | |
| SCHEMBL7496053 | 0.93 | TP53 (0.39) | F2MAOBMAPT | |
| SCHEMBL7546883 | 0.92 | F2 (0.41) | F2 | |
| SCHEMBL7504596 | 0.92 | F2 (0.45) | F2 | |
| SCHEMBL7502292 | 0.89 | F2 (0.36) | F2NMUR2NMUR1 | |
| SCHEMBL6967946 | 0.86 | F2 (0.38) | F2NMUR2NMUR1EPHA2 | |
| SCHEMBL8939655 | 0.85 | F2 (0.47) | F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523308-A | SERINE PROTEASES INHIBITORS; ORAL ANTICOAGULANTS; CHEMICAL INTERMEDIATES; DIPEPTIDES | ORTHO PHARMACEUTICAL CORPORATION | 1996-06-04 | — | — | US | claimed |