SCHEMBL8939614

SCHEMBL8939614

O=C(O)Nc1ccc(C#Cc2ccccc2)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
NPC1 O15118 3/20 0.64
MEN1 O00255 3/20 0.64
KMT2A Q03164 3/20 0.64
KDM4E B2RXH2 2/20 0.64
LMNA P02545 1/20 0.64
MAPT P10636 1/20 0.64
CASP3 P42574 1/20 0.64
SENP7 Q9BQF6 1/20 0.64
HTT P42858 1/20 0.62
ALDH1A1 P00352 1/20 0.59
HPGD P15428 1/20 0.59
CYP2C19 P33261 1/20 0.59
PTPN11 Q06124 4/20 0.53
PTPN1 P18031 2/20 0.50
PTPN6 P29350 2/20 0.50
FFAR1 O14842 2/20 0.50
POLB P06746 1/20 0.50
NLRP3 Q96P20 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2231385 0.84 RAB9A (0.85) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL23880575 0.84 PTPN11 (0.74) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL11117957 0.82 RAB9A (0.57) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL399356 0.81 RAB9A (0.69) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL25736016 0.81 RAB9A (0.61) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL404152 0.80 RAB9A (0.77) RAB9ASMN1; SMN2NPC1MEN1KMT2A
SCHEMBL7634 0.79 EPHX2 (0.70) RAB9ASMN1; SMN2NPC1KMT2AMAPT
Benzene SCHEMBL28162617 0.79 EPHX2 (0.70) RAB9ASMN1; SMN2NPC1KMT2AMAPT
SCHEMBL10778839 0.79 SMN1; SMN2 (0.52) RAB9ASMN1; SMN2NPC1KMT2AMAPT
SCHEMBL19168003 0.79 PTPN1 (0.67) RAB9ANPC1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150274886-A1 Crosslinkable Soluble Aromatic Polyester TICONA LLC 2015-10-01 US claimed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US claimed
US-8853342-B2 Crosslinkable liquid crystalline polymer TICONA LLC (US) 2014-10-07 US claimed
US-20140088247-A1 Crosslinkable Aromatic Polyester TICONA LLC (US) 2014-03-27 US claimed
US-20140088284-A1 Crosslinkable Liquid Crystalline Polymer TICONA LLC (US) 2014-03-27 US claimed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO claimed
CN-108884242-B Prepreg product and composite product comprising fibres and a liquid crystalline thermoset precursor 阿罗特罗皮卡科技公司 2021-11-26 CN disclosed
US-11001013-B2 Pre-preg and composite products comprising fibers and a liquid crystal thermoset precursor ALLOTROPICA TECHNOLOGIES INC. (US) 2021-05-11 US disclosed
EP-3405513-B1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECH INC (US) 2020-03-18 EP disclosed
US-20190039331-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR ALLOTROPICA TECHNOLOGIES INC. 2019-02-07 US disclosed
EP-3405513-A1 PRE-PREG AND COMPOSITE PRODUCTS COMPRISING FIBERS AND A LIQUID CRYSTAL THERMOSET PRECURSOR Allotropica Technologies Inc. (US) 2018-11-28 EP disclosed
CN-108884242-A Preimpregnation product and joint product including fiber and liquid crystal thermosetting precursor 阿罗特罗皮卡科技公司 2018-11-23 CN disclosed
US-20170267824-A1 PREPREG COMPOSITE CONTAINING A CROSSLINKED AROMATIC POLYESTER TICONA LLC 2017-09-21 US disclosed
US-9145519-B2 Crosslinkable aromatic polyester TICONA LLC (US) 2015-09-29 US disclosed
US-8853342-B2 Crosslinkable liquid crystalline polymer TICONA LLC (US) 2014-10-07 US disclosed
US-20140088247-A1 Crosslinkable Aromatic Polyester TICONA LLC (US) 2014-03-27 US disclosed
WO-2014047015-A1 CROSSLINKABLE AROMATIC POLYESTER TICONA LLC (US) 2014-03-27 WO disclosed
US-20140088284-A1 Crosslinkable Liquid Crystalline Polymer TICONA LLC (US) 2014-03-27 US disclosed
US-5489387-A Separation agent comprising acyl- or carbamoyl-substituted polysaccharide DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1996-02-06 US disclosed
US-4966694-A CELLULOSE TRI-BETA-NAPHTHOATE; OPTICAL RESOLUTIONS DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 1990-10-30 US disclosed