Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939936 | 0.99 | HTR2C (0.31) | HTR2CHTR2B | |
| SCHEMBL8939698 | 0.94 | FASN (0.33) | HTR2CHTR2BHTR2AKDM1A | |
| SCHEMBL8940648 | 0.92 | GABRA1 (0.31) | — | |
| SCHEMBL8932645 | 0.92 | KDM1A (0.35) | KDM1A | |
| SCHEMBL8940821 | 0.92 | GABRA1 (0.30) | — | |
| SCHEMBL18718587 | 0.91 | HTR2C (0.33) | HTR2CHTR2BHTR2AKDM1A | |
| SCHEMBL8939896 | 0.91 | KDM1A (0.35) | KDM1A | |
| SCHEMBL8940590 | 0.91 | FASN (0.30) | — | |
| SCHEMBL8940839 | 0.91 | — | — | |
| SCHEMBL8939715 | 0.90 | KDM1A (0.32) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8187494-B2 | Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device | JNC CORPORATION (JP) | 2012-05-29 | — | — | US | disclosed |