SCHEMBL8940058

SCHEMBL8940058

C=CC1CCC(c2ccc(-c3ccc(-c4ccc(OCCC)c(F)c4F)cc3)c(F)c2)OC1

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.37
GABRB2 P47870 2/20 0.37
FPR2 P25090 8/20 0.34
KDM1A O60341 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8940077 0.95 CNR2 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940145 0.95 GABRA1 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940110 0.94 KDM1A (0.37) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940087 0.94 GABRA1 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940202 0.94 GABRA1 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940149 0.94 GABRA1 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL8940357 0.94 GABRA1 (0.34) GABRA1GABRB2FPR2KDM1A
SCHEMBL13579527 0.92 GABRA1 (0.37) GABRA1GABRB2FPR2
SCHEMBL13579375 0.92 GABRA1 (0.37) GABRA1GABRB2FPR2
SCHEMBL13262757 0.92

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
EP-2206695-A1 TETRA- OR PENTA-CYCLIC LIQUID CRYSTALLINE COMPOUND HAVING LATERAL FLUORINE, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT Chisso Corporation (JP) 2010-07-14 EP disclosed