⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1688880 | 0.92 | — | — | |
| SCHEMBL20658161 | 0.80 | THRB (0.47) | — | |
| SCHEMBL6141330 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL2943888 | 0.77 | — | — | |
| SCHEMBL4629365 | 0.77 | THRB (0.50) | — | |
| SCHEMBL25179958 | 0.77 | THRB (0.50) | — | |
| SCHEMBL7147288 | 0.77 | — | — | |
| SCHEMBL21462379 | 0.77 | THRB (0.50) | — | |
| SCHEMBL22268827 | 0.77 | THRB (0.50) | — | |
| SCHEMBL7153949 | 0.77 | THRB (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5565588-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids | ROUSSEL UCLAF (FR) | 1996-10-15 | — | — | US | claimed |
| EP-0263569-B1 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1992-12-09 | — | — | EP | claimed |
| EP-0492495-A2 | Immobilized D-amino acid oxidase and its use for the production of drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | claimed |
| EP-0150350-B1 | CROSS-LINKED POLYMERS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | claimed |
| WO-1988002753-A2 | 9-ALPHA-HYDROXY STEROIDS AND PROCESS FOR THEIR PREPARATION | GIST-BROCADES N.V. (NL) | 1988-04-21 | — | — | WO | claimed |
| EP-0150350-A2 | Cross-linked polymers, process for their manufacture and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-07 | — | — | EP | claimed |
| US-5565588-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing said steroids | ROUSSEL UCLAF (FR) | 1996-10-15 | — | — | US | disclosed |
| US-5352809-A | 9-alpha-hydroxy steroids, process for their preparation, process for the preparation of the corresponding 9(11)-dehydro derivatives and pharmaceutical preparations containing such steroids | GIST-BROCADES N.V. (NL) | 1994-10-04 | — | — | US | disclosed |
| EP-0263569-B1 | 9-alpha-hydroxysteroids, process for their preparation and process for the preparation of the corresponding 9(11)-dehydro-derivatives. | ROUSSEL-UCLAF (FR) | 1992-12-09 | — | — | EP | disclosed |
| EP-0492495-A2 | Immobilized D-amino acid oxidase and its use for the production of drugs | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-01 | — | — | EP | disclosed |
| EP-0150350-B1 | CROSS-LINKED POLYMERS, PROCESS FOR THEIR MANUFACTURE AND USE THEREOF | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-25 | — | — | EP | disclosed |
| EP-0150350-A2 | Cross-linked polymers, process for their manufacture and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-08-07 | — | — | EP | disclosed |