SCHEMBL8940095

SCHEMBL8940095

O=C(/C=C/C(=O)OC(=O)C(O)CO)OC(=O)C(O)CO

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
OR51E2 Q9H255 1/20 0.40
HCAR2 Q8TDS4 3/20 0.32
ATM Q13315 1/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618422 0.85 MAPT (0.49) OR51E2
SCHEMBL15173239 0.84 OR51E2 (0.39) OR51E2
SCHEMBL908373 0.82 LMNA (0.35) OR51E2
SCHEMBL115219 0.82 TSHR (0.45) OR51E2
SCHEMBL93977 0.82 OR51E2 (0.50) OR51E2
SCHEMBL4985589 0.79 OR51E2 (0.48) OR51E2
SCHEMBL6249794 0.79 OR51E2 (0.48) OR51E2
Water SCHEMBL22418485 0.79 OR51E2 (0.55) OR51E2
SCHEMBL5081389 0.77 SMN1; SMN2 (0.46) HCAR2ATM
Ethylene Glycol SCHEMBL3837465 0.77 OR51E2 (0.46) OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119235804-A Carbamazepine pharmaceutical composition and preparation method and application thereof 上海则正医药科技股份有限公司 2025-01-03 CN claimed
CN-118055759-A Miniature tablet containing losartan for pediatric use 米达斯制药有限责任公司 2024-05-17 CN claimed
WO-2023031755-A1 FORMULATIONS, COMPOSITIONS AND METHODS FOR THE DELIVERY OF NEURODEGENERATIVE DRUGS THEREOF AVACA PHARMA PRIVATE LIMITED (IN) 2023-03-09 WO claimed
WO-2023002338-A1 COMPOSITIONS, METHODS OF MAKING AND USING SAME FOR THE DELIVERY OF ULCEROGENIC DRUGS THEREOF AVACA PHARMA PRIVATE LIMITED (IN) 2023-01-26 WO claimed
EP-0516141-B1 Pharmaceutical controlled-release composition with bioadhesive properties RECORDATI CHEM PHARM (CH) 1996-08-14 EP claimed
US-20250375459-A1 METHODS FOR AMELIORATING COGNITIVE IMPAIRMENT USING BILE ACID DERIVATIVES INTERCEPT PHARMACEUTICALS INC (US) 2025-12-11 US disclosed
CN-120021412-A Pharmaceutical composition containing heteroaryloxy naphthalene compounds, and preparation method and application thereof 上海润石医药科技有限公司 2025-05-20 CN disclosed
EP-4547256-A1 METHODS FOR AMELIORATING COGNITIVE IMPAIRMENT USING BILE ACID DERIVATIVES Intercept Pharmaceuticals, Inc. (US) 2025-05-07 EP disclosed
CN-119235804-A Carbamazepine pharmaceutical composition and preparation method and application thereof 上海则正医药科技股份有限公司 2025-01-03 CN disclosed
CN-118055759-A Miniature tablet containing losartan for pediatric use 米达斯制药有限责任公司 2024-05-17 CN disclosed
WO-2024006537-A1 METHODS FOR AMELIORATING COGNITIVE IMPAIRMENT USING BILE ACID DERIVATIVES INTERCEPT PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed
CN-116669749-A Use of cannabidiol for treating psychological disorders 埃米利亚公司 2023-08-29 CN disclosed
WO-2023002338-A1 COMPOSITIONS, METHODS OF MAKING AND USING SAME FOR THE DELIVERY OF ULCEROGENIC DRUGS THEREOF AVACA PHARMA PRIVATE LIMITED (IN) 2023-01-26 WO disclosed
CN-113874023-A Methods of using obeticholic acid for diagnosis and treatment of liver disease 英特塞普特医药品公司 2021-12-31 CN disclosed
CN-113271951-A Methods of using obeticholic acid 英特塞普特医药品公司 2021-08-17 CN disclosed
CN-113226316-A Crystalline forms and processes of lenvatinib besylate 斯索恩有限公司 2021-08-06 CN disclosed
US-5571533-A Controlled-release mucoadhesive pharmaceutical composition for the oral administration of furosemide RECORDATI, S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1996-11-05 US disclosed
EP-0516141-B1 Pharmaceutical controlled-release composition with bioadhesive properties RECORDATI CHEM PHARM (CH) 1996-08-14 EP disclosed
US-5472704-A Particles of active core material coated with controlled release polymer film and mucoadhesive polymer outer layer RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) 1995-12-05 US disclosed
EP-0516141-A1 Pharmaceutical controlled-release composition with bioadhesive properties RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1992-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250375459-A1 METHODS FOR AMELIORATING COGNITIVE IMPAIRMENT USING BILE ACID DERIVATIVES SLC10A1, NR1H4, CHAT OR51E2 4527/4885HCAR2 320/4885ATM 2360/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.