SCHEMBL8940176

SCHEMBL8940176

C/C=C/C1CCC(c2ccc(-c3ccc(-c4ccc(OC)c(F)c4F)cc3)c(F)c2)OC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 2/20 0.32
FPR2 P25090 5/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18718592 0.93 KDM1A (0.33) KDM1A
SCHEMBL8940193 0.91 KDM1A (0.36) KDM1AFPR2
SCHEMBL8940016 0.89 KDM1A (0.32) KDM1AFPR2
SCHEMBL8940420 0.88 FPR2 (0.33) KDM1AFPR2
SCHEMBL8940209 0.87 KDM1A (0.31) KDM1A
SCHEMBL8940270 0.87 HTR2C (0.32)
SCHEMBL8940106 0.87
SCHEMBL8949013 0.87 FPR2 (0.35) KDM1AFPR2
SCHEMBL8940213 0.86 KDM1A (0.31) KDM1AFPR2
SCHEMBL9016368 0.86 CYP3A4 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed
US-8187494-B2 Four- or five-ring liquid crystal compound having lateral fluorine, liquid crystal composition, and liquid crystal display device JNC CORPORATION (JP) 2012-05-29 US disclosed