Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.73 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15630452 | 1.00 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL8940225 | 1.00 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL13752150 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7282832 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9405578 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL3424994 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9405574 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL7289188 | 0.88 | SLC6A3 (0.75) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4996786 | 0.88 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL4996780 | 0.88 | SLC6A3 (0.73) | SLC6A3SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5554626-A | TREATMENT OF PARKINSON*S DISEASE, DRUG ABUSE/DEPENDENCE; COANIE/AMPHETAMINE ADDICTION | NEUROSEARCH A/S (DK) | 1996-09-10 | — | — | US | disclosed |
| US-5444070-A | TREATING A DISEASE OR DISORDER WHICH IS RESPONSIVE TO THE INHIBITION OF DOPAMINE REUPTAKE BY ADMINISTERING A TROPANE DERIVATIVE | NEUROSEARCH A/S (DK) | 1995-08-22 | — | — | US | disclosed |
| US-5374636-A | Antidrug abuse, antidepressants, antiParkinson activity | NEUROSEARCH A/S (DK) | 1994-12-20 | — | — | US | disclosed |
| US-5369113-A | Certain 2,3-diphenyl-2-(1,2,4-oxadiazol-5-yl)tropanes useful as dopamide reuptake inhibitors | NEUROSEARCH A/S (DK) | 1994-11-29 | — | — | US | disclosed |