Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6524963 | 0.98 | MEN1 (0.50) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12391960 | 0.87 | HTR1A (0.43) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL16944246 | 0.85 | HTR1A (0.42) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL3388499 | 0.84 | TSHR (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL22419882 | 0.76 | HTR1A (0.41) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL16940066 | 0.76 | HTR1A (0.36) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL12234839 | 0.76 | HTR1A (0.36) | HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL26072534 | 0.76 | MEN1 (0.46) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL12086392 | 0.75 | HTR1A (0.39) | TSHRALDH1A1HTR1ADRD2HTR2A | |
| SCHEMBL12391950 | 0.74 | HTR1A (0.34) | HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504240-A | HYDROBORATION AND REDUCING AGENTS | ALDRICH CHEMICAL COMPANY, INC. (US) | 1996-04-02 | — | — | US | disclosed |