Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28097079 | 0.91 | THRB (0.51) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL2701652 | 0.90 | THRB (0.46) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL1637662 | 0.90 | THRB (0.46) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| Propene SCHEMBL28137471 | 0.88 | THRB (0.45) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| Butadiene SCHEMBL9316374 | 0.88 | THRB (0.45) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL28149678 | 0.88 | THRB (0.48) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL23636 | 0.88 | THRB (0.48) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL15303703 | 0.87 | THRB (0.40) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL10391726 | 0.86 | THRB (0.47) | THRBTSHRCYP3A4ALDH1A1TP53 | |
| SCHEMBL5884750 | 0.86 | THRB (0.47) | THRBTSHRCYP3A4ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0716669-A1 | LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS | SHELL OIL CO (US) | 1996-06-19 | — | — | EP | claimed |
| WO-1995006681-A1 | LOW DENSITY POROUS CROSSLINKED POLYMERIC MATERIALS | SHELL OIL COMPANY (US) | 1995-03-09 | — | — | WO | claimed |
| US-5340842-A | An addition copolymer consisting of at least one saccharide fatty acid ester as cell control foaming agent; stability, high adsorption; adsorbers/materials/, diapers, wipes | SHELL OIL COMPANY (US) | 1994-08-23 | — | — | US | claimed |