SCHEMBL8940733

SCHEMBL8940733

CCCCCC(Cl)(Cl)N=C=O

nearest known ligand 0.36

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
FDPS P14324 11/20 0.36
SMPD1 P17405 2/20 0.35
GGPS1 O95749 7/20 0.33
CA2 P00918 1/20 0.33
CES2 O00748 1/20 0.31
LPAR1 Q92633 1/20 0.31
LPAR3 Q9UBY5 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL715785 0.83 GGPS1 (0.33) FDPSSMPD1GGPS1
SCHEMBL19371325 0.78 FDPS (0.33) FDPSSMPD1GGPS1CA2
SCHEMBL483529 0.77 FDPS (0.35) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL25176378 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL25170574 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL25225539 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL25170625 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL22472353 0.76 FDPS (0.34) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL11040522 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1
SCHEMBL25176597 0.76 GGPS1 (0.39) FDPSSMPD1GGPS1CES2LPAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113072512-B Preparation method of polyisocyanate 万华化学集团股份有限公司 2022-11-08 CN claimed
CN-113072512-A Preparation method of polyisocyanate 万华化学集团股份有限公司 2021-07-06 CN claimed
JP-8176098-A None JP disclosed
CN-115716906-B Hexamethylene diisocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2025-02-18 CN disclosed
CN-118359791-A Hexamethylene diisocyanate composition stable in long-period storage 万华化学集团股份有限公司 2024-07-19 CN disclosed
CN-115716906-A Hexamethylene diisocyanate composition and preparation method and application thereof 万华化学集团股份有限公司 2023-02-28 CN disclosed
CN-113072512-B Preparation method of polyisocyanate 万华化学集团股份有限公司 2022-11-08 CN disclosed
CN-113072512-A Preparation method of polyisocyanate 万华化学集团股份有限公司 2021-07-06 CN disclosed
JP-H08176098-A UNSATURATED MONOMER AND HIGH REFRACTIVE INDEX RESIN MATERIAL MITSUBISHI CHEM CORP 1996-07-09 JP disclosed