Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | GPR3 | P46089 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585845 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8940850 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8940961 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9586811 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9585891 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9585965 | 1.00 | S1PR1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8940834 | 0.99 | ALDH1A1 (0.47) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9586937 | 0.96 | ALDH1A1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL8940807 | 0.95 | ALDH1A1 (0.48) | S1PR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11731336 | 0.86 | MAPT (0.53) | S1PR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5518656-A | BIS/ALKYLBENZOXAZOLYL/NAPHTHALENE OR 1,5-DIPHENYL-3-STYRYLPYRAZOLINE | NIPPON CHEMICAL WORKS CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |