Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8940588 | 0.89 | ERN1 (0.42) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL9563947 | 0.82 | ALDH1A1 (0.52) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL10118361 | 0.80 | MAPT (0.42) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL1505978 | 0.78 | ERN1 (0.40) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL27760135 | 0.78 | GAA (0.43) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL9332746 | 0.78 | ERN1 (0.58) | ERN1GAAALDH1A1MAPTKDM4E | |
| SCHEMBL4401042 | 0.78 | GAA (0.48) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL29768451 | 0.78 | ERN1 (0.40) | ERN1GAANPC1ALDH1A1TRPV4 | |
| Ammonia Solution, Strong SCHEMBL27985986 | 0.78 | MAPT (0.41) | ERN1GAANPC1ALDH1A1TRPV4 | |
| SCHEMBL13747962 | 0.77 | GAA (0.39) | ERN1GAANPC1ALDH1A1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0700384-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER (US) | 1996-03-13 | — | — | EP | disclosed |
| WO-1994027966-A1 | PROCESS FOR PREPARING AND RESOLVING 2-PHENYL-3-AMINOPIPERIDINE | PFIZER INC. (US) | 1994-12-08 | — | — | WO | disclosed |